Standard

Migraine

near ONECUT2 · rs34653882

Where this position leads

Condition: Migraine

rs34653882 Condition: Migraine Migraine Condition rs34653882 rs34653882 near ONECUT2

What the study found

Who was studied 85,726 European ancestry cases, 803,292 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 7 × 10−12.

How common The G allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 18, band 18q21.31 — between genes, 10.8 kb from ONECUT2.

What each result means

A/A No copy of the version the research linked to Migraine. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Migraine. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Migraine. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs34653882

What is rs34653882?

rs34653882 is a single position in the genome, in or near the near ONECUT2 gene. Published research associates it with migraine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34653882 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

Does having rs34653882 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34653882 come from?

GWAS Catalog, Communications biology 2021, PMID:34294844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Migraine (rs34653882). MyGeneLog™. https://www.mygenelog.com/variants/rs34653882

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