Red blood cell volume distribution width variation in pregnancy
near SMG9 · rs346527
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 98,021 Chinese ancestry individuals; replicated in 46,217 Chinese ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0575 lower (95% confidence interval 0.039-0.076); p = 7 × 10−10.
How common The G allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 19, band 19q13.31 — between genes, 0.2 kb from SMG9.
What each result means
A/ANo copy of the version the research linked to Red blood cell volume distribution width variation in pregnancy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Red blood cell volume distribution width variation in pregnancy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Red blood cell volume distribution width variation in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs346527 is a single position in the genome, in or near the near SMG9 gene. Published research associates it with red blood cell volume distribution width variation in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs346527 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs346527 come from?
GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Red blood cell volume distribution width variation in pregnancy (rs346527). MyGeneLog™. https://www.mygenelog.com/variants/rs346527