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Neonatal cytokine/chemokine levels (maternal genetic effect)

CYP3A4 · rs34642455

What the study found

Who was studied 790 Hispanic, European, Asian, South Asian or African American individuals.

The effect Each copy of the C allele shifted the measure 2.17 lower (95% confidence interval 1.43-2.91); p = 3 × 10−8.

How common The C allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 7, band 7q22.1 — in an intron of CYP3A4.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neonatal cytokine/chemokine levels (maternal genetic effect) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neonatal cytokine/chemokine levels (maternal genetic effect).
T/T Published research associates this genotype with typical/baseline likelihood of Neonatal cytokine/chemokine levels (maternal genetic effect) — no copies of the reported risk allele.
Source

Questions about rs34642455

What is rs34642455?

rs34642455 is a single position in the genome, in or near the CYP3A4 gene. Published research associates it with neonatal cytokine/chemokine levels (maternal genetic effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34642455 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34642455 come from?

GWAS Catalog, Genome Med 2018, PMID:30134952. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neonatal cytokine/chemokine levels (maternal genetic effect) (rs34642455). MyGeneLog™. https://www.mygenelog.com/variants/rs34642455

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