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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 344,292 European ancestry individuals, 118,886 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0274 higher (95% confidence interval 0.023-0.032); p = 4 × 10−32.
Where it sits Chromosome 9, band 9q34.3 — in an intron of INPP5E.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-06-26.
ClinVar record 1293494NM_019892.6(INPP5E):c.1279+131C>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ATwo copies of the version the research linked to Serum alkaline phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum alkaline phosphatase levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum alkaline phosphatase levels. This is the starting point the study compared everyone against.
rs34619169 is a single position in the genome, in or near the INPP5E gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34619169 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34619169 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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