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Appendicular lean mass

ADAMTS14 · rs34616741

What the study found

Who was studied 85,750 European ancestry middle-aged adult individuals.

The effect Each copy of the A allele shifted the measure 0.0707 lower (95% confidence interval 0.049-0.092); p = 8 × 10−11.

How common The A allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 10, band 10q22.1 — in an intron of ADAMTS14.

What each result means

A/A Two copies of the version the research linked to Appendicular lean mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Appendicular lean mass. That is a smaller link than two copies.
G/G No copy of the version the research linked to Appendicular lean mass. This is the starting point the study compared everyone against.
Source

Questions about rs34616741

What is rs34616741?

rs34616741 is a single position in the genome, in or near the ADAMTS14 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34616741 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34616741 come from?

GWAS Catalog, American journal of human genetics 2019, PMID:31761296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Appendicular lean mass (rs34616741). MyGeneLog™. https://www.mygenelog.com/variants/rs34616741

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