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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 20,165 European ancestry cases, 595,231 European ancestry controls.
The effect
Each copy of the C allele carried 1.25 times the odds of acne vulgaris (95% confidence interval 1.21–1.3); p = 3 × 10−35.
How common The C allele had a frequency of about 83% in the people studied.
Where it sits Chromosome 15, band 15q26.1 — in an intron of SEMA4B.
What each result means
C/CTwo copies of the version the research linked to acne vulgaris. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to acne vulgaris. That is a smaller link than two copies.
T/TNo copy of the version the research linked to acne vulgaris. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35132056 · open access
Questions about rs34560261
What is rs34560261?
rs34560261 is a single position in the genome, in or near the SEMA4B gene. Published research associates it with acne vulgaris. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34560261 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34560261 come from?
GWAS Catalog, Nature communications 2022, PMID:35132056. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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