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Ascending thoracic aortic diameter

near RN7SKP155 · rs34557926

What the study found

Who was studied 33,637 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.058 lower (95% confidence interval 0.045-0.072); p = 8 × 10−18.

How common The C allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 8, band 8q24.13 — between genes, 5.9 kb from RN7SKP155.

What each result means

C/C Two copies of the version the research linked to Ascending thoracic aortic diameter. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Ascending thoracic aortic diameter. That is a smaller link than two copies.
T/T No copy of the version the research linked to Ascending thoracic aortic diameter. This is the starting point the study compared everyone against.
Source

Questions about rs34557926

What is rs34557926?

rs34557926 is a single position in the genome, in or near the near RN7SKP155 gene. Published research associates it with ascending thoracic aortic diameter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34557926 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34557926 come from?

GWAS Catalog, Nature genetics 2022, PMID:34837083. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ascending thoracic aortic diameter (rs34557926). MyGeneLog™. https://www.mygenelog.com/variants/rs34557926

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