Standard
Red cell distribution width
ANKRD27 · rs34540877
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Red cell distribution width compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Red cell distribution width.
T/T
Published research associates this genotype with typical/baseline likelihood of Red cell distribution width — no copies of the reported risk allele.
Source
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
Astle WJ,
Elding H,
Jiang T,
Allen D,
Ruklisa D,
Mann AL,
Mead D,
Bouman H,
Riveros-Mckay F,
Kostadima MA,
Lambourne JJ,
Sivapalaratnam S
and 62 more — show all
Downes K,
Kundu K,
Bomba L,
Berentsen K,
Bradley JR,
Daugherty LC,
Delaneau O,
Freson K,
Garner SF,
Grassi L,
Guerrero J,
Haimel M,
Janssen-Megens EM,
Kaan A,
Kamat M,
Kim B,
Mandoli A,
Marchini J,
Martens JHA,
Meacham S,
Megy K,
O'Connell J,
Petersen R,
Sharifi N,
Sheard SM,
Staley JR,
Tuna S,
van der Ent M,
Walter K,
Wang SY,
Wheeler E,
Wilder SP,
Iotchkova V,
Moore C,
Sambrook J,
Stunnenberg HG,
Di Angelantonio E,
Kaptoge S,
Kuijpers TW,
Carrillo-de-Santa-Pau E,
Juan D,
Rico D,
Valencia A,
Chen L,
Ge B,
Vasquez L,
Kwan T,
Garrido-Martín D,
Watt S,
Yang Y,
Guigo R,
Beck S,
Paul DS,
Pastinen T,
Bujold D,
Bourque G,
Frontini M,
Danesh J,
Roberts DJ,
Ouwehand WH,
Butterworth AS,
Soranzo N
Cell · 2016 · PMID 27863252 · open access
Questions about rs34540877
What is rs34540877?
rs34540877 is a single position in the genome, in or near the ANKRD27 gene. Published research associates it with red cell distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34540877 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34540877 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants