A/APublished research associates this genotype with typical/baseline likelihood of Parkinson's disease (familial, age at onset) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Parkinson's disease (familial, age at onset).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Parkinson's disease (familial, age at onset) compared to the general population.
Human molecular genetics · 2016 · PMID 27402877 · open access
Questions about rs344650
What is rs344650?
rs344650 is a single position in the genome, in or near the LHFPL2 gene. Published research associates it with parkinson's disease (familial, age at onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs344650 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs344650 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs344650 come from?
GWAS Catalog, Hum Mol Genet 2016, PMID:27402877. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.