Metabolomic risk score for mild cognitive impairment
AGXT2 · rs344515
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,890 Cuban, Central American, Dominican, Mexican, Puerto Rican, South American ancestry individuals; replicated in 3,149 Cuban, Central American, Dominican, Mexican, Puerto Rican, South American ancestry individuals, 1,032 African American individuals, 3,775 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.192 lower; p = 2 × 10−14.
Where it sits Chromosome 5, band 5p13.2 — in an intron of AGXT2.
What each result means
A/ATwo copies of the version the research linked to Metabolomic risk score for mild cognitive impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Metabolomic risk score for mild cognitive impairment. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Metabolomic risk score for mild cognitive impairment. This is the starting point the study compared everyone against.
Translational psychiatry · 2023 · PMID 37120436 · open access
Questions about rs344515
What is rs344515?
rs344515 is a single position in the genome, in or near the AGXT2 gene. Published research associates it with metabolomic risk score for mild cognitive impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs344515 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs344515 come from?
GWAS Catalog, Translational psychiatry 2023, PMID:37120436. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Metabolomic risk score for mild cognitive impairment (rs344515). MyGeneLog™. https://www.mygenelog.com/variants/rs344515