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Phosphatidylcholine (18:0_18:2) levels

RWDD3-DT · rs34396223

What the study found

Who was studied 7,174 Finnish ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.2 lower (95% confidence interval 0.15-0.25); p = 7 × 10−13.

How common The T allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 1, band 1p21.3 — in an intron of RWDD3-DT.

What each result means

C/C No copy of the version the research linked to Phosphatidylcholine (18:0_18:2) levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Phosphatidylcholine (18:0_18:2) levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Phosphatidylcholine (18:0_18:2) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs34396223

What is rs34396223?

rs34396223 is a single position in the genome, in or near the RWDD3-DT gene. Published research associates it with phosphatidylcholine (18:0_18:2) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34396223 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34396223 come from?

GWAS Catalog, Nature communications 2023, PMID:37907536. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phosphatidylcholine (18:0_18:2) levels (rs34396223). MyGeneLog™. https://www.mygenelog.com/variants/rs34396223

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