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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 85,824 European ancestry individuals, 3,509 African American or Afro-Caribbean individuals, 3,337 East Asian ancestry individuals, 3,098 Hispanic or Latin American individuals.
The effect
Each copy of the A allele shifted the measure 0.022 higher (95% confidence interval 0.014-0.03); p = 2 × 10−8.
How common The A allele had a frequency of about 67% in the people studied.
Where it sits Chromosome 2, band 2q33.1 — in an intron of PLCL1.
What each result means
A/ATwo copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
Nature medicine · 2023 · PMID 37264206 · open access
Questions about rs34388051
What is rs34388051?
rs34388051 is a single position in the genome, in or near the PLCL1 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs34388051 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34388051 come from?
GWAS Catalog, Nature medicine 2023, PMID:37264206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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