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Cortical surface area

ARB2A · rs34322452

What the study found

Who was studied 33,992 European ancestry individuals; replicated in 14,727 European ancestry individuals, 2,943 individuals.

The effect Each copy of the A allele shifted the measure 20.3 higher (95% confidence interval 15.27-25.36); p = 3 × 10−15.

How common The A allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 5, band 5q15 — in an intron of ARB2A.

What each result means

A/A Two copies of the version the research linked to Cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cortical surface area. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cortical surface area. This is the starting point the study compared everyone against.
Source

Questions about rs34322452

What is rs34322452?

rs34322452 is a single position in the genome, in or near the ARB2A gene. Published research associates it with cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34322452 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34322452 come from?

GWAS Catalog, Science (New York, N.Y.) 2020, PMID:32193296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical surface area (rs34322452). MyGeneLog™. https://www.mygenelog.com/variants/rs34322452

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