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Who was studied 16,407 European ancestry cases, 762,486 European ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 2 × 10−13.
Where it sits Chromosome 9, band 9q34.3 — in an intron of INPP5E.
What each result means
A/ANo copy of the version the research linked to Cutaneous squamous cell carcinoma. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Cutaneous squamous cell carcinoma. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Cutaneous squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2024 · PMID 38182794 · open access
Questions about rs34302850
What is rs34302850?
rs34302850 is a single position in the genome, in or near the INPP5E gene. Published research associates it with cutaneous squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs34302850 linked to?
On MyGeneLog this position is linked to Cutaneous Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs34302850 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs34302850 come from?
GWAS Catalog, Communications biology 2024, PMID:38182794. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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