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Glypican-5 levels (GPC5.4991.12.1)

GPC5 · rs342702

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.8 lower (95% confidence interval -0.76--0.84); p = 5 × 10−233.

How common The T allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 13, band 13q31.3 — in an intron of GPC5.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Glypican-5 levels (GPC5.4991.12.1) — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glypican-5 levels (GPC5.4991.12.1).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glypican-5 levels (GPC5.4991.12.1) compared to the general population.
Source

Questions about rs342702

What is rs342702?

rs342702 is a single position in the genome, in or near the GPC5 gene. Published research associates it with glypican-5 levels (gpc5.4991.12.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs342702 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs342702 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glypican-5 levels (GPC5.4991.12.1) (rs342702). MyGeneLog™. https://www.mygenelog.com/variants/rs342702

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