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CD74 protein levels

ZNF184 · rs34196306

Where this position leads

Condition: Celiac Disease

rs34196306 Condition: Celiac Disease Celiac Disease Condition rs34196306 rs34196306 ZNF184

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0937 higher (95% confidence interval 0.076-0.111); p = 2 × 10−31.

How common The C allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — in an intron of ZNF184.

What each result means

C/C Two copies of the version the research linked to CD74 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to CD74 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to CD74 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs34196306

What is rs34196306?

rs34196306 is a single position in the genome, in or near the ZNF184 gene. Published research associates it with cd74 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34196306 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs34196306 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34196306 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CD74 protein levels (rs34196306). MyGeneLog™. https://www.mygenelog.com/variants/rs34196306

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