Standard

Childhood asthma with severe exacerbations

IL33 · rs340933

Where this position leads

Condition: Asthma

rs340933 Condition: Asthma Asthma Condition rs340933 rs340933 IL33

What the study found

Who was studied 2,866 European ancestry cases, 65,415 European ancestry controls.

The effect Each copy of the G allele carried 1.37 times the odds of Childhood asthma with severe exacerbations (95% confidence interval 1.26-1.49); p = 2 × 10−13.

Where it sits Chromosome 9, band 9p24.1 — between genes, 69.5 kb from RANBP6.

What each result means

G/G Two copies of the version the research linked to Childhood asthma with severe exacerbations. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Childhood asthma with severe exacerbations. That is a smaller link than two copies.
T/T No copy of the version the research linked to Childhood asthma with severe exacerbations. This is the starting point the study compared everyone against.
Source

Questions about rs340933

What is rs340933?

rs340933 is a single position in the genome, in or near the IL33 gene. Published research associates it with childhood asthma with severe exacerbations. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs340933 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs340933 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs340933 come from?

GWAS Catalog, Nature communications 2020, PMID:33328473. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Childhood asthma with severe exacerbations (rs340933). MyGeneLog™. https://www.mygenelog.com/variants/rs340933

← See all variants