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Monocyte percentage of white cells

S1PR3 · rs34075341

Where this position leads

Condition: Blood Cell Counts

rs34075341 Condition: Blood Cell Counts Blood Cell Counts Condition rs34075341 rs34075341 S1PR3

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0576 lower (95% confidence interval 0.039-0.076); p = 9 × 10−10.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 9, band 9q22.1 — a missense change in S1PR3.

What each result means

A/A Two copies of the version the research linked to Monocyte percentage of white cells. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Monocyte percentage of white cells. That is a smaller link than two copies.
G/G No copy of the version the research linked to Monocyte percentage of white cells. This is the starting point the study compared everyone against.
Source

Questions about rs34075341

What is rs34075341?

rs34075341 is a single position in the genome, in or near the S1PR3 gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs34075341 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs34075341 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34075341 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells (rs34075341). MyGeneLog™. https://www.mygenelog.com/variants/rs34075341

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