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Mammographic density (dense area)

MAFF · rs34066050

What the study found

Who was studied 24,579 European ancestry females.

The effect Each copy of the G allele shifted the measure 5.53 z score lower; p = 3 × 10−8.

How common The G allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 22, band 22q13.1 — between genes, 0.1 kb from MAFF.

What each result means

A/A No copy of the version the research linked to Mammographic density (dense area). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mammographic density (dense area). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mammographic density (dense area). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs34066050

What is rs34066050?

rs34066050 is a single position in the genome, in or near the MAFF gene. Published research associates it with mammographic density (dense area). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs34066050 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs34066050 come from?

GWAS Catalog, Breast cancer research : BCR 2022, PMID:35414113. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Mammographic density (dense area) (rs34066050). MyGeneLog™. https://www.mygenelog.com/variants/rs34066050

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