1 17122210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 129,680 East Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0431 higher (95% confidence interval 0.029-0.057); p = 6 × 10−10.
Where it sits Chromosome 5, band 5q35.3 — in an intron of ADAMTS2.
What each result means
C/CTwo copies of the version the research linked to FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to FEV1/FVC ratio. That is a smaller link than two copies.
T/TNo copy of the version the research linked to FEV1/FVC ratio. This is the starting point the study compared everyone against.
rs340121 is a single position in the genome, in or near the ADAMTS2 gene. Published research associates it with fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs340121 linked to?
On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.
Does having rs340121 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs340121 come from?
GWAS Catalog, Nature genetics 2026, PMID:41565855. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 17122210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
FEV1/FVC ratio (rs340121). MyGeneLog™. https://www.mygenelog.com/variants/rs340121