Sensitive

Venous thromboembolism

RORA · rs340009

Where this position leads

Condition: Venous Thromboembolism

rs340009 Condition: Venous Thromboembolism Venous Thromboembolism Condition rs340009 rs340009 RORA

What the study found

Who was studied 7,177 European ancestry cases, 1,059,740 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0335 lower (95% confidence interval 0.022-0.045); p = 3 × 10−8.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 15, band 15q22.2 — in an intron of RORA.

What each result means

A/A Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.
C/C No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.
Source

Questions about rs340009

What is rs340009?

rs340009 is a single position in the genome, in or near the RORA gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs340009 linked to?

On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.

Does having rs340009 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs340009 come from?

GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Venous thromboembolism (rs340009). MyGeneLog™. https://www.mygenelog.com/variants/rs340009

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