Sensitive

Prostate cancer

near RFX6 · rs339321

Where this position leads

Condition: Prostate Cancer

rs339321 Condition: Prostate Cancer Prostate Cancer Condition rs339321 rs339321 near RFX6

What the study found

Who was studied 3,963 Sub-Saharan African ancestry cases, 3,509 Sub-Saharan African ancestry controls.

The effect Each copy of the G allele shifted the measure 0.278 higher (95% confidence interval 0.2-0.36); p = 1 × 10−11.

Where it sits Chromosome 6, band 6q22.1 — between genes, 6.2 kb from RFX6.

What each result means

A/A No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs339321

What is rs339321?

rs339321 is a single position in the genome, in or near the near RFX6 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs339321 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs339321 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs339321 come from?

GWAS Catalog, Nature genetics 2024, PMID:39358599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs339321). MyGeneLog™. https://www.mygenelog.com/variants/rs339321

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