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Whole amygdala volume

MAST2 · rs33931638

What the study found

Who was studied 35,292 European ancestry individuals, 227 African ancestry individuals, 380 South Asian ancestry individuals, 115 East Asian ancestry individuals, 338 individuals.

The effect Each copy of the A allele shifted the measure 28.8 lower (95% confidence interval 20.4-37.26); p = 2 × 10−11.

Where it sits Chromosome 1, band 1p34.1 — a missense change in MAST2.

What each result means

A/A Two copies of the version the research linked to Whole amygdala volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Whole amygdala volume. That is a smaller link than two copies.
G/G No copy of the version the research linked to Whole amygdala volume. This is the starting point the study compared everyone against.
Source

Questions about rs33931638

What is rs33931638?

rs33931638 is a single position in the genome, in or near the MAST2 gene. Published research associates it with whole amygdala volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs33931638 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs33931638 come from?

GWAS Catalog, Biological psychiatry 2024, PMID:37391117. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Whole amygdala volume (rs33931638). MyGeneLog™. https://www.mygenelog.com/variants/rs33931638

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