G/GPublished research associates this genotype with typical/baseline likelihood of Renal cell carcinoma — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Renal cell carcinoma.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Renal cell carcinoma compared to the general population.
Nature communications · 2026 · PMID 42000752 · open access
Questions about rs33925946
What is rs33925946?
rs33925946 is a single position in the genome, in or near the near ZBTB42 gene. Published research associates it with renal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs33925946 linked to?
On MyGeneLog this position is linked to Renal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs33925946 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs33925946 come from?
GWAS Catalog, Nature communications 2026, PMID:42000752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.