0 41111Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon0Apple0Others1Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 5,093 European ancestry cases, 444,966 European ancestry controls, 160 East Asian ancestry cases, 151,846 East Asian ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.146 lower (95% confidence interval 0.11-0.19); p = 6 × 10−13.
Where it sits Chromosome 19, band 19q13.2 — in an intron of CYP2S1.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Nasal polyps compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Nasal polyps.
T/TPublished research associates this genotype with typical/baseline likelihood of Nasal polyps — no copies of the reported risk allele.
rs338593 is a single position in the genome, in or near the CYP2S1 gene. Published research associates it with nasal polyps. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs338593 linked to?
On MyGeneLog this position is linked to Chronic Rhinosinusitis with Nasal Polyps. The research behind each link, and its sources, are set out on that condition page.
Does having rs338593 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs338593 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 41111Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon0Apple0Others1Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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