Who was studied 164,339 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0301 lower (95% confidence interval 0.021-0.039); p = 1 × 10−11.
How common The C allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 3, band 3q21.2 — in an intron of KALRN.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Plateletcrit compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Plateletcrit.
T/TPublished research associates this genotype with typical/baseline likelihood of Plateletcrit — no copies of the reported risk allele.
rs332507 is a single position in the genome, in or near the KALRN gene. Published research associates it with plateletcrit. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs332507 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs332507 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs332507 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.