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Eosinophil count

WAC · rs332161

What the study found

Who was studied 365,954 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.033 lower (95% confidence interval 0.023-0.043); p = 1 × 10−12.

How common The G allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 10, band 10p12.1 — in an intron of WAC.

What each result means

C/C No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs332161

What is rs332161?

rs332161 is a single position in the genome, in or near the WAC gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs332161 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs332161 come from?

GWAS Catalog, Frontiers in immunology 2022, PMID:35935937. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil count (rs332161). MyGeneLog™. https://www.mygenelog.com/variants/rs332161

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