near PPP1R3B · rs330071
Where this position leads
Condition: Osteoarthritis
What the study found
Who was studied 6,725 European ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.144 higher; p = 2 × 10−16.
Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.
rs330071 is a single position in the genome, in or near the near PPP1R3B gene. Published research associates it with diacylglycerol (12:0/18:0) (model 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2026, PMID:42069741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diacylglycerol (12:0/18:0) (Model 2) (rs330071). MyGeneLog™. https://www.mygenelog.com/variants/rs330071