Standard
HDL cholesterol levels
LRP4 · rs326214
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of HDL cholesterol levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with HDL cholesterol levels.
G/G
Published research associates this genotype with typical/baseline likelihood of HDL cholesterol levels — no copies of the reported risk allele.
Source
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
Spracklen CN,
Chen P,
Kim YJ,
Wang X,
Cai H,
Li S,
Long J,
Wu Y,
Wang YX,
Takeuchi F,
Wu JY,
Jung KJ
and 103 more — show all
Hu C,
Akiyama K,
Zhang Y,
Moon S,
Johnson TA,
Li H,
Dorajoo R,
He M,
Cannon ME,
Roman TS,
Salfati E,
Lin KH,
Guo X,
Sheu WHH,
Absher D,
Adair LS,
Assimes TL,
Aung T,
Cai Q,
Chang LC,
Chen CH,
Chien LH,
Chuang LM,
Chuang SC,
Du S,
Fan Q,
Fann CSJ,
Feranil AB,
Friedlander Y,
Gordon-Larsen P,
Gu D,
Gui L,
Guo Z,
Heng CK,
Hixson J,
Hou X,
Hsiung CA,
Hu Y,
Hwang MY,
Hwu CM,
Isono M,
Juang JJ,
Khor CC,
Kim YK,
Koh WP,
Kubo M,
Lee IT,
Lee SJ,
Lee WJ,
Liang KW,
Lim B,
Lim SH,
Liu J,
Nabika T,
Pan WH,
Peng H,
Quertermous T,
Sabanayagam C,
Sandow K,
Shi J,
Sun L,
Tan PC,
Tan SP,
Taylor KD,
Teo YY,
Toh SA,
Tsunoda T,
van Dam RM,
Wang A,
Wang F,
Wang J,
Wei WB,
Xiang YB,
Yao J,
Yuan JM,
Zhang R,
Zhao W,
Chen YI,
Rich SS,
Rotter JI,
Wang TD,
Wu T,
Lin X,
Han BG,
Tanaka T,
Cho YS,
Katsuya T,
Jia W,
Jee SH,
Chen YT,
Kato N,
Jonas JB,
Cheng CY,
Shu XO,
He J,
Zheng W,
Zheng W,
Wong TY,
Huang W,
Kim BJ,
Tai ES,
Mohlke KL,
Sim X
Human molecular genetics · 2017 · PMID 28334899
Questions about rs326214
What is rs326214?
rs326214 is a single position in the genome, in or near the LRP4 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs326214 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs326214 come from?
GWAS Catalog, Hum Mol Genet 2017, PMID:28334899. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants