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Serum 25-Hydroxyvitamin D levels (conditioned on BMI)

MEF2A · rs325384

What the study found

Who was studied 417,580 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.014 lower (95% confidence interval -0.018--0.01); p = 1 × 10−10.

How common The C allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 15, band 15q26.3 — in an intron of MEF2A.

What each result means

C/C Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). This is the starting point the study compared everyone against.
Source

Questions about rs325384

What is rs325384?

rs325384 is a single position in the genome, in or near the MEF2A gene. Published research associates it with serum 25-hydroxyvitamin d levels (conditioned on bmi). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs325384 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs325384 come from?

GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (conditioned on BMI) (rs325384). MyGeneLog™. https://www.mygenelog.com/variants/rs325384

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