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High density lipoprotein cholesterol levels

CD36 · rs3211938

What the study found

Who was studied 99,432 Admixed African or African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.134 higher (95% confidence interval 0.12-0.15); p = 6 × 10−51.

How common The G allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 7, band 7q21.11 — a stop-gain change in CD36.

What ClinVar records

Classification Conflicting classifications of pathogenicity for Platelet-type bleeding disorder 10, Malaria, cerebral, susceptibility to; criteria provided, conflicting classifications (1 of 4 stars, 4 submitters), last evaluated 2023-09-11. ClinVar record 13536 NM_001001548.3(CD36):c.975T>G (p.Tyr325Ter)

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

G/G Two copies of the version the research linked to High density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to High density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to High density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs3211938

What is rs3211938?

rs3211938 is a single position in the genome, in or near the CD36 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3211938 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3211938 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

High density lipoprotein cholesterol levels (rs3211938). MyGeneLog™. https://www.mygenelog.com/variants/rs3211938

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