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Who was studied at least 506,594 individuals (MTAG boosted by type 2 diabetes samples).
The effect
Each copy of the T allele shifted the measure 0.03 higher (95% confidence interval 0.03-0.03); p = 9 × 10−9.
How common The T allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 11, band 11q13.1 — in a non-coding transcript of MALAT1.
What each result means
C/CNo copy of the version the research linked to Periodontitis / loose teeth (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Periodontitis / loose teeth (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Periodontitis / loose teeth (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in endocrinology · 2022 · PMID 36778599 · open access
Questions about rs3200401
What is rs3200401?
rs3200401 is a single position in the genome, in or near the MALAT1 gene. Published research associates it with periodontitis / loose teeth (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3200401 linked to?
On MyGeneLog this position is linked to Periodontitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3200401 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3200401 come from?
GWAS Catalog, Frontiers in endocrinology 2022, PMID:36778599. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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