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Linoleic acid levels

MARK4 · rs3178166

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−10.

Where it sits Chromosome 19, band 19q13.32 — in the 3′ untranslated region of MARK4.

What each result means

A/A No copy of the version the research linked to Linoleic acid levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Linoleic acid levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Linoleic acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3178166

What is rs3178166?

rs3178166 is a single position in the genome, in or near the MARK4 gene. Published research associates it with linoleic acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3178166 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3178166 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Linoleic acid levels (rs3178166). MyGeneLog™. https://www.mygenelog.com/variants/rs3178166

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