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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 401 European ancestry cases, 17,164 European ancestry controls, 23 African American ancestry cases, 352 African American ancestry controls, 257 Pakistani ancestry cases, 4,453 Pakistani ancestry controls.
The effect
Each copy of the T allele carried 3.70 times the odds of Ischemic stroke (large artery atherosclerosis) (95% confidence interval 2.33-5.88); p = 4 × 10−8.
Where it sits Chromosome 1, band 1p32.3 — in an intron of CDKN2C.
What each result means
A/ANo copy of the version the research linked to Ischemic stroke (large artery atherosclerosis). This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Ischemic stroke (large artery atherosclerosis). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Ischemic stroke (large artery atherosclerosis). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3176471 is a single position in the genome, in or near the CDKN2C gene. Published research associates it with ischemic stroke (large artery atherosclerosis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3176471 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3176471 come from?
GWAS Catalog, Stroke 2016, PMID:26732560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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