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Metabolite levels

DVL2 · rs314251

Where this position leads

Condition: Blood Metabolite Levels

rs314251 Condition: Blood Metabolite Levels Blood Metabolite Levels Condition rs314251 rs314251 DVL2

What the study found

Who was studied 1,954 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.182 higher (95% confidence interval 0.12-0.24); p = 3 × 10−9.

How common The A allele had a frequency of about 85% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of DLG4.

What each result means

A/A Two copies of the version the research linked to Metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Metabolite levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Metabolite levels. This is the starting point the study compared everyone against.
Source

Questions about rs314251

What is rs314251?

rs314251 is a single position in the genome, in or near the DVL2 gene. Published research associates it with metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs314251 linked to?

On MyGeneLog this position is linked to Blood Metabolite Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs314251 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs314251 come from?

GWAS Catalog, Human molecular genetics 2020, PMID:31628463. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Metabolite levels (rs314251). MyGeneLog™. https://www.mygenelog.com/variants/rs314251

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