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Triglyceride levels

RFC2 · rs3135688

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0305 lower (95% confidence interval 0.024-0.037); p = 5 × 10−12.

How common The C allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — a synonymous change in RFC2.

What each result means

C/C Two copies of the version the research linked to Triglyceride levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Triglyceride levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglyceride levels. This is the starting point the study compared everyone against.
Source

Questions about rs3135688

What is rs3135688?

rs3135688 is a single position in the genome, in or near the RFC2 gene. Published research associates it with triglyceride levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3135688 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3135688 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels (rs3135688). MyGeneLog™. https://www.mygenelog.com/variants/rs3135688

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