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LTA protein levels

near NFKBIL1 · rs3135043

What the study found

Who was studied 489 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.408 lower (95% confidence interval 0.3-0.52); p = 2 × 10−12.

Where it sits Chromosome 6, band 6p21.33 — between genes, 5.6 kb from NFKBIL1.

What each result means

A/A Two copies of the version the research linked to LTA protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to LTA protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to LTA protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs3135043

What is rs3135043?

rs3135043 is a single position in the genome, in or near the near NFKBIL1 gene. Published research associates it with lta protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3135043 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3135043 come from?

GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

LTA protein levels (rs3135043). MyGeneLog™. https://www.mygenelog.com/variants/rs3135043

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