Standard

Hand grip strength

near HLA-DQB1 · rs3134986

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hand grip strength — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hand grip strength.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hand grip strength compared to the general population.

Source

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank

Tikkanen E, Gustafsson S, Amar D, Shcherbina A, Waggott D, Ashley EA, Ingelsson E

Scientific reports · 2018 · PMID 29691431 · open access

Questions about rs3134986

What is rs3134986?

rs3134986 is a single position in the genome, in or near the near HLA-DQB1 gene. Published research associates it with hand grip strength. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3134986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3134986 come from?

GWAS Catalog, Sci Rep 2018, PMID:29691431. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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