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BTN2A1 protein levels

near HLA-B · rs3134792

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.11 higher (95% confidence interval 0.1-0.12); p = 2 × 10−198.

How common The G allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 9.3 kb from HLA-B.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of BTN2A1 protein levels compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with BTN2A1 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of BTN2A1 protein levels — no copies of the reported risk allele.
Source

Questions about rs3134792

What is rs3134792?

rs3134792 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with btn2a1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3134792 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3134792 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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BTN2A1 protein levels (rs3134792). MyGeneLog™. https://www.mygenelog.com/variants/rs3134792

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