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Ankle-brachial index

SYBU · rs3133941

What the study found

Who was studied 3,637 Caribbean ancestry individuals; replicated in up to 8,527 European ancestry individuals, 2,362 African American individuals, 1,447 Hispanic/Latino individuals.

The effect Each copy of the A allele shifted the measure 0.018 lower (95% confidence interval 0.012-0.024); p = 2 × 10−8.

How common The A allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 8, band 8q23.2 — between genes, 11.9 kb from SYBU.

What each result means

A/A Two copies of the version the research linked to Ankle-brachial index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Ankle-brachial index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Ankle-brachial index. This is the starting point the study compared everyone against.
Source

Questions about rs3133941

What is rs3133941?

rs3133941 is a single position in the genome, in or near the SYBU gene. Published research associates it with ankle-brachial index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3133941 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3133941 come from?

GWAS Catalog, Scientific reports 2019, PMID:31388106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Ankle-brachial index (rs3133941). MyGeneLog™. https://www.mygenelog.com/variants/rs3133941

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