Standard

Left-handedness

TUBB · rs3132584

What the study found

Who was studied 1,766,671 European ancestry individuals.

The effect Each copy of the T allele carried 0.95 times the odds of Left-handedness; p = 6 × 10−25.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in an intron of TUBB.

What ClinVar records

Classification Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2018-06-26. ClinVar record 1240826 NM_178014.4(TUBB):c.57+87G>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

G/G No copy of the version the research linked to Left-handedness. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Left-handedness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Left-handedness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3132584

What is rs3132584?

rs3132584 is a single position in the genome, in or near the TUBB gene. Published research associates it with left-handedness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3132584 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3132584 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:32989287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Left-handedness (rs3132584). MyGeneLog™. https://www.mygenelog.com/variants/rs3132584

← See all variants