Sensitive

Estimated glomerular filtration rate in diabetes

TRIM27 · rs3132374

What the study found

Who was studied 70,762 European ancestry individuals, 20,967 African American individuals.

The effect Each copy of the C allele shifted the measure 0.959 higher (95% confidence interval 0.64-1.27); p = 3 × 10−9.

How common The C allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — between genes, 2.3 kb from TRIM27.

What each result means

C/C Two copies of the version the research linked to Estimated glomerular filtration rate in diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Estimated glomerular filtration rate in diabetes. That is a smaller link than two copies.
G/G No copy of the version the research linked to Estimated glomerular filtration rate in diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs3132374

What is rs3132374?

rs3132374 is a single position in the genome, in or near the TRIM27 gene. Published research associates it with estimated glomerular filtration rate in diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3132374 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3132374 come from?

GWAS Catalog, Nature communications 2019, PMID:31451708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate in diabetes (rs3132374). MyGeneLog™. https://www.mygenelog.com/variants/rs3132374

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