4 434226122222Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 720 European ancestry female cases, 2,337 European ancestry female controls; replicated in 1,846 European ancestry female cases, 1,825 European ancestry female controls.
The effect
Each copy of the A allele carried 2.36 times the odds of Systemic lupus erythematosus (95% confidence interval 2.11-2.64); p = 2 × 10−52.
How common The A allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of MSH5-SAPCD1.
What each result means
A/ATwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs3131379
What is rs3131379?
rs3131379 is a single position in the genome, in or near the HLA region gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3131379 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs3131379?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs3131379 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3131379 come from?
GWAS Catalog, Nat Genet 2008, PMID:18204446. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 434226122222Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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