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Mean platelet volume

HCG20 · rs3131057

What the study found

Who was studied 164,454 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0307 lower (95% confidence interval 0.024-0.038); p = 8 × 10−17.

How common The C allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 2.1 kb from HCG20.

What each result means

C/C Two copies of the version the research linked to Mean platelet volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean platelet volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet volume. This is the starting point the study compared everyone against.
Source

Questions about rs3131057

What is rs3131057?

rs3131057 is a single position in the genome, in or near the HCG20 gene. Published research associates it with mean platelet volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3131057 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3131057 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume (rs3131057). MyGeneLog™. https://www.mygenelog.com/variants/rs3131057

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