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Hepatitis B

HLA-C · rs3130542

Where this position leads

Condition: Chronic Hepatitis B

rs3130542 Condition: Chronic Hepatitis B Chronic Hepatitis B Condition Topic: Infection and immunity Infection and immunity Topic rs3130542 rs3130542 HLA-C

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hepatitis B compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:24162738)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hepatitis B. (GWAS Catalog, Nat Genet 2013, PMID:24162738)
G/G Published research associates this genotype with typical/baseline likelihood of Hepatitis B — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:24162738)

Source: GWAS Catalog, Nat Genet 2013, PMID:24162738

What people read about alongside this

Infection and immunity6

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs3130542

What is rs3130542?

rs3130542 is a single position in the genome, in or near the HLA-C gene. Published research associates it with hepatitis b. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3130542 linked to?

On MyGeneLog this position is linked to Chronic Hepatitis B. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs3130542?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (6 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3130542 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3130542 come from?

GWAS Catalog, Nat Genet 2013, PMID:24162738. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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