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Who was studied 412,937 British ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0155 lower (95% confidence interval 0.011-0.02); p = 2 × 10−10.
How common The G allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of PSORS1C3.
What each result means
A/ANo copy of the version the research linked to Parental longevity (mother's attained age). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Parental longevity (mother's attained age). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Parental longevity (mother's attained age). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3130507 is a single position in the genome, in or near the PSORS1C3 gene. Published research associates it with parental longevity (mother's attained age). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3130507 linked to?
On MyGeneLog this position is linked to Human Lifespan and Longevity. The research behind each link, and its sources, are set out on that condition page.
Does having rs3130507 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3130507 come from?
GWAS Catalog, Aging 2017, PMID:29227965. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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