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Creatinine clearance

SLC22A2 · rs3127572

What the study found

Who was studied 23,355 European ancestry males.

The effect Each copy of the A allele shifted the measure 2.03 higher (95% confidence interval 1.41-2.65); p = 2 × 10−10.

How common The A allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 6, band 6q25.3 — in an intron of SLC22A2.

What each result means

A/A Two copies of the version the research linked to Creatinine clearance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine clearance. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine clearance. This is the starting point the study compared everyone against.
Source

Questions about rs3127572

What is rs3127572?

rs3127572 is a single position in the genome, in or near the SLC22A2 gene. Published research associates it with creatinine clearance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3127572 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3127572 come from?

GWAS Catalog, Kidney international 2026, PMID:42302930. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine clearance (rs3127572). MyGeneLog™. https://www.mygenelog.com/variants/rs3127572

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