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Electrocardiogram morphology (amplitude at temporal datapoints)

KCNJ2 · rs312755

What the study found

Who was studied 63,706 European and unknown ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0476 lower (95% confidence interval 0.035-0.06); p = 2 × 10−13.

How common The T allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 17, band 17q24.3 — between genes, 109.4 kb from CALM2P1.

What each result means

A/A No copy of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Electrocardiogram morphology (amplitude at temporal datapoints). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs312755

What is rs312755?

rs312755 is a single position in the genome, in or near the KCNJ2 gene. Published research associates it with electrocardiogram morphology (amplitude at temporal datapoints). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs312755 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs312755 come from?

GWAS Catalog, Cell systems 2020, PMID:32916098. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Electrocardiogram morphology (amplitude at temporal datapoints) (rs312755). MyGeneLog™. https://www.mygenelog.com/variants/rs312755

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