Standard
Thyrotoxic hypokalemic periodic paralysis
KCNJ16 · rs312691
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Thyrotoxic hypokalemic periodic paralysis compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:22863731)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Thyrotoxic hypokalemic periodic paralysis. (GWAS Catalog, Nat Genet 2012, PMID:22863731)
T/T
Published research associates this genotype with typical/baseline likelihood of Thyrotoxic hypokalemic periodic paralysis — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:22863731)
Source
Genome-wide association study identifies a susceptibility locus for thyrotoxic periodic paralysis at 17q24.3
Cheung CL,
Lau KS,
Ho AY,
Lee KK,
Tiu SC,
Lau EY,
Leung J,
Tsang MW,
Chan KW,
Yeung CY,
Woo YC,
Cheung EY
and 5 more — show all
Nature genetics · 2012 · PMID 22863731
Questions about rs312691
What is rs312691?
rs312691 is a single position in the genome, in or near the KCNJ16 gene. Published research associates it with thyrotoxic hypokalemic periodic paralysis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs312691 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs312691 come from?
GWAS Catalog, Nat Genet 2012, PMID:22863731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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