4 5453246221227Reads by AI crawlersClaude5ChatGPT3Google · Gemini2Perplexity4Meta AI6Microsoft · Copilot2Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 1,012 Han Chinese ancestry cases, 1,362 Han Chinese ancestry controls; replicated in 3,624 Han Chinese ancestry cases, 12,197 Han Chinese ancestry controls, 1,806 European ancestry cases, 3,256 European ancestry controls.
The effect
Each copy of the A allele carried 1.22 times the odds of Atopic dermatitis; p = 6 × 10−12.
How common The A allele had a frequency of about 58% in the people studied.
Where it sits Chromosome 1, band 1q21.3 — in an intron of CCDST.
What each result means
A/ATwo copies of the version the research linked to Atopic dermatitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Atopic dermatitis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Atopic dermatitis. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs3126085
What is rs3126085?
rs3126085 is a single position in the genome, in or near the FLG gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3126085 linked to?
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs3126085?
Subjects that appear in the title or abstract of the same papers as this rsID include allergies (7 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs3126085 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3126085 come from?
GWAS Catalog, Nat Genet 2011, PMID:21666691. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5453246221227Reads by AI crawlersClaude5ChatGPT3Google · Gemini2Perplexity4Meta AI6Microsoft · Copilot2Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.